WVE-007 and the Expanding Role of Metabolic Treatments in Mental Health Care
The landscape of metabolic medicine has changed significantly over the past several years, largely driven by the impact of GLP-1 receptor agonists.
Understand psychiatric medications with clear, evidence-informed guidance from South Chesapeake Psychiatry. These articles cover how medications work, common benefits and side effects, dosing considerations, monitoring, drug interactions, and the questions clients should discuss with a psychiatric provider. Topics may include antidepressants, mood stabilizers, antipsychotics, ADHD medications, anxiety treatments, long-acting injectables, and newer options such as Cobenfy, Caplyta, Auvelity, and SPRAVATO®. Medication choice is never one-size-fits-all. Diagnosis, medical conditions, other prescriptions, previous treatment response, tolerability, pregnancy considerations, substance use, and personal goals can all affect the safest plan. This content is for education and should not be used to start, stop, or change medication without professional guidance. Our Chesapeake, Virginia practice provides psychiatric evaluations and ongoing medication management for adults across Hampton Roads. Follow the related service link on an article to learn more about the appropriate care pathway, or schedule an appointment for an individualized review of symptoms, history, risks, and treatment options.

The landscape of metabolic medicine has changed significantly over the past several years, largely driven by the impact of GLP-1 receptor agonists.

For decades, we've grappled with the challenge of treating major depressive disorder (MDD)—particularly in clients who also experience anxious distress. Add to that the limitations of current treatments, delayed onset of action, and tolerability issues, and it’s no wonder that innovation in this space is urgently needed

There are few drugs that are Food and Drug Administration (FDA) indicated first line for Generalized Anxiety Disorder (GAD). Selective Serotonin Inhibitors (SSRIs) such as Lexapro (escitalopram), approved in 2005, and Paxil (paroxetine), approved in 1999, by the FDA.

The conversation around lumateperone (Caplyta) in bipolar depression has become more nuanced with new data and, frankly, more complicated in clinical practice. A recent meta-analysis in the Journal of Psychopharmacology confirmed what many of us already knew at the bedside:

GM-2505 (bretisilocin) is a short-acting psychedelic-class compound now in late-stage development for major depressive disorder. A look at the early data, AbbVie’s investment, and what it could mean for clients who have not responded to standard antidepressants.

GLP-1 medications are an effective tool for weight loss, especially when combined with dietary and behavioral changes. These drugs mimic a natural gut hormone, GLP-1, released after eating to help regulate appetite, digestion, and blood sugar. While digestive side effects are common, serious complications are rare but should be monitored.
Schedule an appointment today to get diagnosed, receive a prescription, and continue your journey towards mental peace.
